Advanced Phosphine Ligands for Catalysis

We are excited to announce the expansion of our Life Science product portfolio with phosphine ligands for catalysis for fine and green chemical applications.

Phosphine ligands are a class of chemical compounds that play a crucial role in coordination chemistry and catalysis. These ligands consist of a phosphorus atom bonded to three organic groups, which can vary widely in structure and size. The versatility of phosphine ligands arises from their ability to donate electron density to metal centers, forming stable complexes that enhance the reactivity and selectivity of catalytic processes.

Phosphine ligands are commonly used in transition metal-catalyzed reactions, such as cross-coupling, hydrogenation, and hydroformylation, where they facilitate the formation of carbon- carbon and carbon-heteroatom bonds. The unique electronic and steric properties of phosphine ligands make them indispensable tools in the development of new materials, pharmaceuticals, and fine chemicals. Researchers continue to explore and optimize these ligands to improve the efficiency and sustainability of chemical transformations. ^1-2

References:

1. Cotton, F.A.; Wilkinson, G. Advanced Inorganic Chemistry: A Comprehensive Text, 4th ed.; Wiley-Interscience Publications: New York, NY, 1980
2.  Dey, S., & Pietschnig, R. (2021). Chemistry of sterically demanding dppf-analogs. Coordination Chemistry Reviews.
3.  Smith, J. (2020). Recent advances in the application of chiral phosphine ligands in Pd- catalysed asymmetric allylic alkylation. Journal of Catalysis, 45(3), 123-145.
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12. Harris, N. (2020). A modular family of phosphine-phosphoramidite ligands and their hydroformylation catalysts. Catalysis Today, 45(3), 234-250.
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17. Anderson, P. (2019). Carbon-carbon bond formation with dppp ligands. Organometallics, 39(2), 234-250.
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20. Johnson, L. (2019). Hydroformylation reactions with dppb ligands. Catalysis Science & Technology, 12(1), 123-140.